Showing posts with label NAS. Show all posts
Showing posts with label NAS. Show all posts

Saturday, September 21, 2013

Dying life unworthy of wartime penicillin was Life unworthy of Life

"all Life is worthy of Penicillin"


The infamous term "Life unworthy of Life", created by a German psychiatrist Alfred Hoche in the 1920s , is generally thought of as bring used exclusively by the Nazis.

Used by them during a Total War to justify killing everyone from working class Aryan babies with developmental issues to the entire Jewish population of Europe.

But the term had a much greater transnational appeal than that .

Prominent American psychiatrist Foster Kennedy thought , in 1941 and 1942, during that same Total War, that the USA would be justified in killing its little Aryan babies with developmental issues.

Shamefully, America's leading psychiatric journal actually agreed with him and only one psychiatrist disputed his thesis.

And the Allies' medical establishment, led by Dr Chester Keefer and his NAS committee, used this idea to justify denying SBE-curing penicillin to young people dying of SBE all over the Allied world,  because they felt that even a cured SBE patient was still useless to the Total War effort.

("Life judged unworthy of Penicillin.")

By contrast, Henry Dawson and a handful of other doctors worldwide supported, and fought for, the notion that "All Life is worthy of Penicillin" - even in , particularly in , a Total War supposedly  fought precisely against the evil idea that some Life was, ipso facto, unworthy of Life.....

Thursday, July 25, 2013

Aktion 4F : something done to 4Fs, rather than something done for 4Fs ?

For years, I have thought and written of Dr Henry Dawson's efforts to try and save the lives of young SBE patients ,"The 4Fs of the 4Fs" , as if it was a sort of counterpoint to Nazi Germany's efforts to kill similar chronically ill people, the infamous Aktion T4 campaign.

His own Aktion 4F as a sort of counterblast to their Aktion T4.

But Dawson wasn't actually directly opposing the German Nazis' murderously utilitarian disposal of humans judged useless consumers of badly needed resources in a Total War.

He was combating similar notions held by the powerful in the Anglo-American medical establishment.

The OSRD , the NAS and the MRC all judged SBE to be a "militarily unimportant disease" and refused to allow any penicillin be diverted to saving its patients.

This despite Dawson demonstrating over and over that penicillin was the only thing that could cure this hitherto invariably fatal disease dubbed "the Polio of the Poor".

So in a way, the Allied treatment of the SBE 4Fs , along with their diverting penicillin away from badly wounded frontline troops in the Mediterranean towards otherwise fit soldiers who had deliberately contracted VD to avoid combat , could be see as exact counterparts to how the Nazis behaved in similar medical situations.

(For example, secretly killing Eastern Front soldiers rendered permanently mentally ill in combat to free up medical beds and supplies for soldiers judged able to return to battle eventually.)

In which case, the co-ordinated campaign , around the Allied world , from the US to Canada to Britain to Australia , to deny penicillin to SBE cases, can be seen as being the true Aktion 4F.

Food for thought....

Monday, January 28, 2013

How wartime penicillin's American miracle cures were censored - and why


From early in 1942, American medical journal editors and authors joined scientific journal editors and authors already being "self censored".

Like them, they were asked (virtually required) to submit all articles they were uncertain about, to a NAS/NRC advisory for vetting before printing or submitting.

Supposedly the NAS medical sub-committee was only censored the chemistry of penicillin , but in fact this wasn't consistently imposed until March 1943,when it fell in line with the UK's more legally formal move in this direction.

Between January 1942 till late in 1943, this system's real ambition was to successfully keep every "miracle cure" by penicillin out of medical and scientific  media - and thus, by reverse osmosis, out of the daily press.

If the American public didn't hear about this miracle drug, then the chemistry-savvy Germans won't either ---- at least not before D-Day, or so the thought went.

I think the key for this method's success was that the OSRD/CMR/COC controlled (a) all the significant new strains and all the new information on how to make penicillin in mass qualities, (b) controlled all supplies of the resulting therapeutic penicillin (c) and as well was busy dangling $500 million in high-overhead contracts to cash and equipment starved university administrators.

So it could successfully tell the university researchers, commercial penicillin firms and the medical accredited investigators, peep one word and no more penicillin/ penicillin information/ cash.

Informally, the OSRD/CMR/COC tried to fend off all requests for stories on this rumoured new wonder drug from non-science journalists, who they had no hold over.

Science journalists - hello William l Laurence ! - were already totally self-embedded in this self censorship. (Color me surprised ...)

General reporters also read popular science stories for possible leads, so with none coming forth on penicillin, they actually made very few such requests.

Of course when a *Hearst* *city desk editor*  got a *Pulitzer* for *spot news reporting*  for saving the life of a baby with the miracle cure penicillin (and modestly reporting the story as well) , all that changed.

(I always thought the real miracle was the Pulitzer Committee giving a prize to a Hearst paper, the arch enemy of George Pulitzer. That and a city desk editor breaking a Pulitzer-worthy foot leather news story without ever leaving his desk (or phone.)

But what I am not sure of , was Byron Price ever asked by the OSRD/CMR's Dr A.N. Richards to amend his codebooks to ask editors to avoid any any mention of penicillin.

I have a request on this out to a real expert on the American experience with self censorship in WWII....

Sunday, January 6, 2013

Howard Florey sole hero of 1944 American national radio play on Penicillin

Here, Howard Florey rules !
Du Pont's Cavalcade of America  on NBC was a very well financed American national radio and later tv show, popular before and after WWII (1935-1957), that as Marcel Lafollette points out , often featured heroes from medicine and science.

Not surprising then that the series featured an half hour show on "The Story of Penicillin" as soon as the censors would let it : which interestingly enough was April 24th 1944  --- starring Howard Florey as the one-and-only who brought us the miracle of penicillin !

(CALV 440424 380 The Story of Penicillin : episode 380, April 24 1944 is very easy to stream or download from the internet.)

Which is to say this half hour national show aired at a time when the OSRD-AMA-NAS triad was still successfully holding back all press interest in penicillin the miracle (by claiming the triad had legal censorship powers that it actually didn't possess.)

Could it be that even the powerful OSRD had to bow before the enough more powerful chemical giant, in part because it was a prime contractor of the A-Bomb ?

But what I  find so interesting about this show - beyond the fact that I do not recall reading about it from any penicillin historian's writing - is that it clearly announces at its onset that its one and only star is "Howard Florey".

Was the show an attempt to discredit Pfizer's sudden success  with non-chemically produced penicillin ?


(Because of all the months of the six years of war, April 1944 was the one I'd been most inclined to credit Pfizer's John L Smith as the man who finally brought us penicillin.)

Because that months of all months was the very first month that billions of units of the hitherto invisible miracle suddenly started pouring out of his rapidly-improvised Marcy Avenue ice plant cum biological penicillin brewery.)

Perhaps the triad felt a need to suddenly burnish the reputation of the big loser in the race to provide penicillin for D-Day :  that loser being synthetic penicillin and Florey's synthetic efforts at Oxford University.

 And believe me, having listened to as much of this half hour show as I could stand, Florey is indeed portrayed as the one and only star of this miracle of medicine.

Florey has an entire army of fans among present-day historians claiming he was elbowed out the fame-feeding-trove by that big mean bully Alec Fleming.

I have always found this hard to stomach.

Florey, in fact, was seemingly born with at least four sharp elbows of his own.

He also had a strong reputation, as a scientist, of being as ready to use his fists to win scientific arguments as  Fred Banting or Vannevar Bush ever did.

I wonder if his academic defenders will still howl " he wuz robbed" after listening to this old radio show ?

Tuesday, January 1, 2013

The 180 degree flip of wartime penicillin : from secret weapon of war to public weapon of propaganda

War is not at all like the playing fields of Eton , many reports to the contrary.

Both sides get advance notice of the time, place and nature of the activity in sports - and there is a strictly enforced set of rules.

By contrast, a successful military offensive operation is far more than half won if it is kept secret to the last moment and beyond.

Convince your foe you plan this Spring's big push there , after the roads have dried and then attack here - when the roads are still muddy - and he might still think it a feint even when your troops are in fact about to knock down the doors of his command centre.

Surprise and secrecy can often beat much higher qualities and quantities of  equipment, manpower and leadership --- if most of a weak force is concentrated in a narrow sector of the enemy's lines  at a time the enemy doesn't expect a major attack.

This need for surprise and secrecy applies to military activity off the battle field as well.

If - as happened all the time in the Pacific Campaign- both sides were down to 10% effective strength due to all the rest laid low by endemic local infections , the battle is almost certainly won if a secret cure-all like DDT clears up the insect source of those infections.

Because the exclusive use of DDT by only one side could enable it to send 50% of its tinier force into battle and win.

But only if DDT's abilities remain secret.

DDT was not strictly speaking "secret" ---- its chemical formula and method of manufacture was revealed in the public scientific literature back in 1874 and again in 1940 in a Swiss patent from Geigy.

But the Japanese hadn't seen those scientific reports or if so, hadn't grasped their military significance.

But even the stupidest Japanese general could correctly access urgent Japanese diplomatic cables indicating that the American domestic press was raving about the miracle success of DDT in clearing malaria from its endemic regions in the southern states of America.

So DDT was kept as secret as possible and more fundamentally , was not made available for civilian use during WWII.

This despite the fact that it was easy and cheap to make and very stable in storage - for the cost of one or two B-29s, the country's agricultural zones could all be sprayed by DDT and the resulting greater farm productivity would well repay the cost of the DDT factories.

Crops - as well as guns - win wars too, it could be argued.

But in fact, the productivity side of Total War was totally ignored over the secrecy side of Total War.

It was similar with Penicillin.

 The key reason that striking, dramatic, heart-stopping successes in dragging civilian bodies back from the grave's edge in 1942-1943 were not permitted to be published by the AMA-OSRD-NAS triad was because this would indirectly alert the world to the military life-saving abilities of penicillin.

Wesley Spink did not rock the boat - unlike Henry Dawson


(See Wesley Spink's dramatic first success in July 1942 with seven year old "JE" - a heart-warming case which was not allowed to be published/publicized until April 1945, for a vivid example.)

Publicizing civilian cures would equalize its effects on the war if both sides, suitably alerted, then employed it freely.

Even if the health-restoring ability of penicillin made the war economy far more productive than the cost of setting up penicillin plants would take out of it ---- and this resulting extra productivity was devoted to making more weapons.

Because, at least in theory , both sides would see their economies expand equally - returning everything to the position it was before penicillin became widely public.

So instead, the Allies hoped to synthesize penicillin so that it was both cheap and abundant (like DDT) but also like DDT, they planned not to release it to the public, but use it as a military weapon - a secret medical weapon - exactly as DDT used.

But the heart-warming story of Baby Patricia in August 1943 let the cat out of the bag, as this local story in New York 'broke wide' , not just stateside but all around the world.

Now not just every civilian in the world wanted it for their sick relative like yesterday but military chiefs across the globe awoke (15 years late !) to the military potential of the miracle cure.

The chiefs of the American military medicine triad (and their equally smarmy British counterparts) pouted ---- but clever people in the Offices of War Information in both Allied nations resolved to make a virtue of necessity.

Baby Patty got her penicillin over the heads of the triad, but now official penicillin would be rushed by American military bombers to saving dying kids all over the world and the effort highly publicized in the process.

It would say to friend, foe and neutral alike that unlike those nasty life-denying Nazis, the Allies cared : oh how they cared.

Henry Dawson must have snickered at the blatant dishonesty in
this abrupt volte-face, but he was very glad lives were being saved however it came about and that the "unlimited potential" of the life-saving mold was at long last being released....




Tuesday, December 18, 2012

Was there a Parran-Hearst Telegram ? (You provide the penicillin, I'll provide the pictures)

"Operator, get me Washington, tell 'em I'm from Hearst..."
There is no firm evidence that Citizen Hearst ever sent that infamous telegram to the famous war artist Frederic Remington in Cuba.

We all know which telegram:  the one where Remington is sent out to illustrate the ongoing civil war in Cuba, but finds all is quiet and begs to go home.

Hearst supposedly telegraphs him to stay : "(If) you furnish the pictures, I'll furnish the war."


Hearst proceeds to puff up the accidental explosion on board the battleship The Maine as an act of sneaky warfare by the Spanish, ("Remember Pearl Harbour" 50 years ahead of schedule) and the rest is history: Yellow Journalism's finest moment.

Or is it ?

For a start, that particular telegram was apparently never sent.

But did the aging Hearst later intervene with US Surgeon General Thomas Parran in August 1943, to get penicillin to a dying baby girl in Manhattan ?

Was this Yellow Journalism's finest moment ?

The Pulitzer Committee apparently felt so - and it is worth noting that Pulitzer and Hearst were the most bitter of bitter enemies.

Consider what we know (or think we know).

Supposedly the whole thing started with a phone call from the distraught father (Lawrence J Malone) of a dying two year old girl called Patricia Malone, made to the city desk editor of the Hearst media empire's flagship newspaper, the New York Journal-American.

Actually Malone quickly fades back into the wallpaper , as do the nominal doctors for the baby girl.

Because in fact, Malone was set up for the call by a crippled Italian-American surgical resident named Dante Colitti, then working at the tiny Lutheran Hospital in upper Manhattan, about a mile from pioneering penicillin doctor Henry Dawson's hospital, Columbia Presbyterian.

The little girl was dying of blood poisoning and normally a surgical staffer - a mere resident at that - has no place in treatment decisions for that sort of illness.

But Colitti was raised right, with a good moral education and he couldn't stand by and let her die, when he knew that not a mile away, Henry Dawson was dragging babies like her back from the grave with his Floor G penicillin.

And Colitti had no cause to love the New York medical establishment which supported the limiting of penicillin to curing VD cases among the unfaithful husbands and boyfriends of the combat corps.

In the 1930s, he had been rejected from attending any New York medical school, by an informal quota system designed to keep out Catholics and Italians.

 (And Jews and Blacks and Asians and Women. Colitti's parents were recent immigrants to America).

Colitti had a permanently bent spine as a result of childhood TB and had to use crutches so it was probably the excuse given him for his rejection.

But Colitti knew that Henry Dawson, just a mile north of him, was working with a doctor who used crutches thanks to polio and another doctor who was missing an arm.

The only real difference was that these were Protestant men, with native-born parents.

Colitti paid a private medical college in Massachusetts to get his MD degree but no New York hospital would recognize any degree not granted by one of the quota-oriented establishment schools.

It was a closed loop.

But WWII led to a desperate shortage of medical staff and even New York's medical establishment had to let people like Colitti in to do the lowest medical jobs, at least until the war was over.

But the highly morally minded Colitti felt that if they had displayed no charity towards a cripple, that did not mean he would follow suit.

Hence his setting up of the phone call to the Hearst paper : he knew exactly who would cause the most noise.

The Journal-American photo-journalists were then world famous for their large, vivid, gripping front page photographs and a dying baby story was just made for their skills.

The Hearst editor got no where ( says the AP press agency) with the OSRD's Dr Richards or with the NAS Committee on Chemical Therapeutics.

But somehow or other the newspaper knew of the ongoing conflict between those who felt we could best win the war ("Hearts & Minds") through well publicized Social Medicine versus those that felt that secretive and rationed War Medicine would save more scarce resources for "Guns & Bullets".

Because the newspaper ultimately got the penicillin it needed from that supply reserved for the US Public Health Services (at that time, it only had a tiny amount of penicillin and it was only normally used for treating cases of VD among merchant seamen.)

Released by drug company Squibb upon the direct order of Thomas Parran, US Surgeon General and head of the US Public Health Services (then a relatively small and powerless body compared to its status today.)

Parran versus Weed over the fate of wartime penicillin


Parran was the de facto head of the Social Medicine forces, while the NAS's Lewis Weed was the voice of War Medicine.

Did Hearst or his senior staff know of this ongoing debate and approach Parran directly, dismissing his concerns about tackling the all-powerful OSRD and NAS by reminding him he had no love for the NAS's Weed anyway , and that if he would only provide the penicillin vials, Hearst photographers would provide the poignant pictures.

Yellow Journalism and the Yellow Magic then proceeded to make beautiful music together : because the Patty Malone Story ultimately spelled the end to the Age of Modernity ...

Sunday, December 2, 2012

The Allied battle for the world's 'hearts and minds' : NS-born Henry Dawson's patient-penicillin vs OSRD war-penicillin

Army is - wrongly - blamed for her SBE death
The idea that successful American governments need first to win over the 'hearts and minds' of people, before they rush to impose their objectives by legal and military fiat is an old, old , old one.

Presidents John Adams used the phrase "hearts and mind" in this sense early in the 19th century, long before Presidents FDR, Kennedy and Johnson made it famous in the 20th century - and before recent presidents George W Bush and Obama dragged it out of the archives to use in this century.

(And to share the blame around, their wartime Ally Britain also used the phrase during its 1950s war in Malaysia.)

When American finally joined The Coalition of the Willing  (December 1941), many of the world's nations still remained strictly neutral in the battle against Nazi evil , or were, at best,  nominal friends but in reality merely laying back on the oars.

The world's largest, richest, most militarily-advanced economies in the world (America and the British Commonwealth) had a real job on their hands trying to convince the neutrals (all much smaller and weaker than these two superpowers) that their interests would not be subsumed before the interests of these global colossus.

Unhelpfully, America and Britain's scientific and medical elite - centred in the American National Academy of Science (NAS) and the British Medical Research Council (MRC)  made the job much harder.

Reactionaries of all stripes (from Germany to America) had been determined to roll back the1930s move to Social Medicine (the claim that more poor people got sick than rich people because they were too poor to pay for adequate housing, food or routine medical care).

However, the dire effects of the Great Depression had put wind behind Social Medicine's sails and confounded the reactionaries.

Now - Thank God ! - war, or even just the possibility of war, gave the reactionaries new hope.

 Hitler killed off his first "useless feeder" the same week that he declared war on the Poles and soon his Aktion T4 program was killing Germany's weakest and smallest members by the tens of thousands.

In America, people like Dr Lewis Weed (a mid-level medical researcher) dropped his unsuccessful research to become a war-medicine advocate at the NAS and its action-oriented NRC (National Research Council).

War medicine wins opening rounds against social medicine


He locked horns with Dr Thomas Parran, the American Surgeon General from 1936 to 1948, who was a strong (and powerfully-positioned) advocate of social medicine.

A war medicine proponent advocates that any nation at war - even the richest, least attacked nation at war - needs to divert resources normally assigned to civilian medicine towards making bullets instead.

 In addition, much more money would have to be spent providing for the high medical requirements of an activity (war) whose stated aim is maiming and killing people on muddy fields miles away from the nearest hospital.

Limited research dollars would have to focus on war-related  medical needs ( such as finding new ways to keep factory workers and bomber pilots alert for long hours) and put before finding  new ways to keep elderly retirees alive) .

War medicine is, in a very real sense, 'eugenics in uniform' : the best citizens (those that are tested and rated physically and mentally to be A1) end up in the military and get top notch medical care at no cost.

Those citizens who fail these tests and end up as 4F, are second rate eugenically and get second rate medical care during the war.

Proudly promote this concept to the outside world - and America's still relatively free press during WWII did just that - and it comes across quite differently in those neutral nations still sitting on the fence with regards to whole-heartedly backing the Allied cause.

As individuals, the elites in these neutral nations could see themselves as A1s  --- but as nationalistically minded citizens they could only see their nations as 4Fs in America's eyes : mere inconvenient dirt beneath their advancing wheels.

When the Patty Malone vs Marie Barker debate broke in the United States media (basically, scarce penicillin for dying civilians : yes or no ?) , it broke even bigger overseas, as worried American and British diplomats noted.

Heartless or caring : the public image of the Allied cause had reached past the unimportant front pages and onto the most important page of any newspaper or magazine --- the women's page : home to Doctor Mom.

It suddenly mattered what the mothers and parents and grandparents from neutral nations thought of America and Britain's harsh dictates on penicillin.

Put your small neutral nation, say Eire or Turkey, in the place of the unfortunate Marie Barker and then ask yourself, how would you feel to just be Marie Barker-like 'incidental collateral damage' , on the pathway to the ultimate Allied Victory ?

And the Home Front within the Allied nations was just as caustic about their own governments' inactions : 'penicillin the miracle cure' had been around for 15 years and still no one in charge had bothered making enough of it for all ?

Don't the bosses know "there's a war on" ???!!!

And let us set this debate (occurring between the late Summer of 1943 and the early Spring of 1944) in its full context.

The western Allies still hadn't invaded Europe and left the heavy lifting of killing German soldiers to the beleaguered Russians.

Instead they were busy bombing Europe into rubble : busily killing civilians from both Axis and neutral nations alike.

The Germans and Allies had co-operated on censoring the results of the fire-bombing of Hamburg of July 1943, (right before the story of little Patty Malone broke) but on-site reports from neutral Swedish journalists had laid the whole horrific affair out on the newspaper pages of the world.

It had led to considerable unease - in neutral country and allied country alike.

Hadn't FDR himself raged that the bombing of civilians was a crime against all humanity and now weren't the Americans and British far out-doing the earlier Nazi efforts to bomb enemy and neutral civilians ?

Allied fire bombing of  innocent babies in occupied Europe - denying life-saving penicillin to innocent young moms in America so that their unfaithful husbands in Italy could be get a quicker ( via penicillin) cure for the Clap - it all didn't seem morally right.

Perhaps surprisingly, the American Army revealed far greater political and cultural savvy on this matter than American doctors and scientists were capable of.

The Army was sick and tired of being blamed for hogging all the penicillin and refusing to give any to the nation's dying babies.

'For Christ's Sake', they could rightfully protest, 'we can't get anywhere enough penicillin for our own dying boys, and we hadn't even heard of this stuff penicillin till a few months ago --- you ask the drug companies and the doctors what they were doing with the stuff for the last 15 years !'

Somewhere in the American Army Air Force some bright mind (s) decided to solve both PR problems (the fire bombing uproar and the penicillin uproar) at one stroke.

(And before you ask, no .)

No academic historian has yet brought us the true story behind this highly imaginative response: I see a great PhD thesis for some bright light.)

Soon, American Army "heavy" bombers were pulled off their bombing practises and were sent out on a still risky flight (because at top speed and at night) "pounding" across country with a tiny 8 grams of penicillin (instead of the normal 8000 pounds of TNT) to deliver to a dying ten pound patient.

Upon arrival, Klieg lights lit the tarmac as an ambulance, along a police escort with blazing lights and piercing sirens, raced to the hospital and the waiting doctor and patients.

Need I add to this purple-prosed drama that, thoughtfully, the local press had been notified well ahead of time ?

Quickly Army bombers were even on far more perilous missions of mercy, dangerously new cross-ocean flights, from places like San Francisco  all the way to Brisbane Australia or from New York to Havana, --- to save dying children.

In 1943, Martin Henry Dawson was dying ,but not quite dead yet, not by a long shot...


Life-saving penicillin had moved 180 degrees from being censored and rationed to being the subject of  radio, newsreel and pamphlet propaganda as an example - the example - of the better things ahead if only all joined in to hasten the Allied Cause.

Neutrals could reassure themselves that just like with dying babies and Martin Henry Dawson's useless-mouthed SBE patients, the Allies would do right by all, as they were doing so now for the least of these.

The Allied battle for the world's hearts and minds, had been won (unexpectedly) by the proponents of social medicine - thanks largely to the example of Martin Henry Dawson.

And decades before Joni Mitchell and Woodstock, the American Army Air Force itself turned its shotgun bombers into butterflies, above a wondering nation and world....

Friday, April 27, 2012

(Houses of) PEER REVIEW

   The House of Lords is a chamber of sober second thoughts, where men and women (Peers) (aged in visage and grey in hair) review proposed new ideas, from the vantage point of honored expertise and authority.
   This sounds a lot like the National Academy of Science (America's NAS)
which is a perpetually self-appointing/self-anointing body of aged scientists, much honored for their expertise and authority, pronouncing upon the gravest scientific questions facing the nation.
   Britain's Royal Society does much the same and most of the world's prominent scientific nations employ a similar model.
   "Peer" is such an ambiguous word.
   One is judged by a jury of one's peers, for example : bog-ordinary citizens like yourself, with no occupational or professional interest in crime or justice.
   But the aristocracy are Peers, peers with a capital "P" , and they are presumed to be anything but ordinary, in fact the very antithesis of ordinary.
   A scientist's proposed journal article, grant request or application for tenure is judged by "peer-review".
   In theory, it is via a jury of people very much like the scientist. In practice the jury is often made up of Peers - scientists much superior in ranking to the supplicant scientist.
   Top scientists, and the world's top professionals, are not just the aristocracy of their world.
   They are the aristocracy of our world : the aristocracy of the world's successful response to the trauma of the 1832 Reform Act and similar legislation.
    And to the rise of the Romantic Era, with its threat of the untutored,un-peer-reviewed, Genius and un-peer-reviewed self-made entrepreneur/celebrity....