FDR and Churchill beat Hitler and Tojo - and then they tried to oppose Henry Dawson...

Martin "Henry" Dawson, a dying doctor.

A lapsed Scottish Presbyterian, but of the old school, the kind  not easily stopped, not when they believed they were duty-bound to do what was right.

A lapsed Calvinist on a catholic mission.

 For Dawson's goal was "Penicillin-for-all".

Particularly at the height of a Total War in which - if you believed the newspapers - his Allied nation opposed the Nazis mostly for their nasty habit of mentally dividing the world in the deserving elect and the non-deserving non-elect.

Of course, in fact,  much of the Allied world mentally did the same - and publicly opposing Dawson's goal merely exposed this awkward fact.

Poor Frank and Winnie when they took on Henry : they simply never stood a chance....

Gladys Hobby : a Calvinist, on a catholic mission...

From September 1940 till December 1943, Dr Gladys Hobby, a devout Presbyterian on a catholic mission ("Penicillin-for-all") , daily visited the Green wards of Columbia-Presbyterian hospital, where the young victims of green SBE waited out their inevitable deaths.

Daily, she held aloft before them a petri dish just aglow with radiated golden penicillium mold, as if it were some marvelous medical monstrance.

As she and her tiny team undoubtedly believed it was.

Pen !!!! Stat !!!!!!!

In the house of the beta-lactams there are many mansions and one might think the most modest one might be occupied by the oldest beta-lactam, the only begetter , the original,  penicillin G.

But it 'taint necessarily so' .

Talking to an emergency ward nurse recently I asked her if they ever used penicillin G much these days.

"Oh my yes ",she said, but added with a smile, "we don't call it penicillin G any more."

"What do you call it then?" , I asked.

"We call it 'Pen Stat' and we say it like we might say 'Code Blue' ..."

Nice to know it is still in the medical armoire and still pulled out whenever the going gets tough and the tough get going : Pen !!!!! Stat !!!!!!

The very smallest Manhattan Project improved the lives of ten billion people

That is an awful lot of us , being positively affected by so few of them.

Many people today would like to do something to make our world a better place but are overwhelmed by the seemingly impossible odds against having any visible effect.

Take heart !

There was never more than three other people at a time involved with Dr Martin Henry Dawson in his five year long quest to bring forth  'penicillin for all'.

His tiny project had no government grants grants nor much enthusiastic institutional support from his own university.

 Even Dawson's immediate bosses opposed his efforts - but this was nothing to the resistance he got from the Anglo-American medical establishment.

That medical establishment was firmly enmeshed within the wartime governments of "win the war at all costs (to human rights)" FDR and Churchill.

Dawson himself was dying the whole time of his quest.

Dying of a particularly debilitating disease (Myasthenia Gravis , MG) , well before the days when patients with it could expect to make their way through semi-normal days.

Economics as if human survival really matters

Unbridled growth, even at the cost of burning to death in our own carbon wastes.

This is what the mantra of "ever bigger is ever better" is leading us to.

What it is not leading to is ever greater happiness.

For if the richest and most powerful among us are not happy, who on earth can be ?

Some apparently.

They live and work in smaller walkable communities without - thanks to the likes of Skype and the internet - feeling at all cut off from the great wide world and distant friends and kin.

They use less carbon energy than you or I not because they restrain themselves like monks but because their life is set up spatially to use and need less carbon energy.

They don't miss what they don't need.

More green energy is not the solution to our carbon addiction : more, more, more is never much of a permanent solution - in tumour growth or in real world economics.

We must develop full happy lifestyles where we need less energy to be well off and happy.

Many small communities in the past developed some of the ways to do so ---- often centuries and millenniums ago.

But before Internet and telegraphs and radio , it came at the price of emotional isolation.

Marry the new Internet and those centuries old ways of living compactly and what will be actually born will be hard to predict - but I feel at least confident that it can't be any worse than the route-to-hell we are now taking ....

Penicillin is not Avastin, but it could have been...

My book - The smallest Manhattan Project  - is about us , all 10 billion of us , here today or years dead, whose lives have been improved by the advent of inexpensive penicillin.

In a sense, this book is a rarity : one written from the patient's eye view of how that drug came to be ; a welcome change after decades of endless books exclusively devoted to how penicillin looked to the people who discovered and developed it.

Penicillin is frequently called the Miracle Drug but few consider that its biggest medical miracle was really in fact its cost, or rather 'lack of cost'.

Because the diseases that penicillin treats are contagious,  patients too poor to afford a cure remains a reservoir of the most virulent strains, waiting to infect the rest of us.

There actually were methods of preventing much of these diseases before the development of penicillin : they included the ready availability of good jobs, good food, cleaner and bigger homes, greater social respect.

Baring that, only the worldwide availability of a drug that would cure those diseases once they started up, at a price that almost all could readily afford , could reduce these diseases from being endemic or epidemic to just names in a dusty medical textbook.

That is why I can say, with absolute assurance, that even those of us who have never had a single treatment of beta-lactam (penicillin family) antibiotics are in better health today because the grandparent of them all, Penicillin G , is water cheap - literally a lifesaver "too cheap to meter" .

But it almost didn't happen , we almost lost "inexpensive penicillin".

We almost got an expensively patented synthetic drug more akin to Avastin and all those other $100,000 a year plus medications.

"The smallest Manhattan Project" is the story of a doctor ( himself slowly dying of another unrelated disease) who sacrificed his own health to see penicillin from the patient's point of view.

His name should be honoured for all time.

This, despite the fact that he did not discover penicillin and then neglect it (Fleming) nor did he start its re-discovery and eventual development, albeit while pursuing a pathway that nearly killed off that development (Florey).

Dr Martin Henry Dawson, for that was his name, merely said penicillin should be made available - now! - for every single patient whose life could be saved by it , even during the height of a Total War .

Nay, he went much, much further.

Dawson in fact said all should have access to life-saving penicillin, particularly in the middle of a Total War.

That was because that war was supposedly being fought against one opponent in particular, solely because that opponent's core philosophy said that 'some lives are more worthy than others'.

How could we continue to conduct that war with any moral vigour when our own medical establishment was 'me-tooing' Hitler's doctors ?

Now the mantra 'Penicillin for all who needed it regardless of their income level or skin colour' in the mid-1940s meant its mass production, given the vast amount of infectious disease endemic in those years.

And mass production has its myriad ways of driving production costs down, down , down --- as happily happened in the case of Penicillin G in almost textbook manner.

'Penicillin for all' quickly became 'inexpensive penicillin for all' and once that happened, penicillin began to work almost like the way a good public health vaccine program should work : the treatment of the many ultimately offering 'herd protection' to all the rest of us, free of charge.

Insulin is another drug frequently called a miracle drug.

But the sad fact is that it is far more common today than it was beforeinsulin was discovered, for a variety of reasons.

By contrast, the names of all those bacterial household scourges that so terrified our mothers and grandmothers are not even known to most of us under the age of 50, and most doctors practising today have never seen a case of them.

And that is just the sort of modern day miracle that Dawson's mantra of 'penicillin for all' can produce.

For the complex truth is that our choice of medical ethics has economic consequences and these in turn feedback and have medical consequences.

The case of what the mantra of 'penicillin for all' ultimately led to should be taught in every health economics and health ethics oriented university department for just those very reasons....

The light of the littlest red lighthouse can light up the world better than that of the greatest grey bridge

I wonder if Marjorie and Henry Dawson ever read the tale of The Little Red Lighthouse to their youngest child before Henry died in mid-1945 ?

That small and seemingly powerless-feeling child, born in 1941, was of the right age to especially appreciate the special message of the classic children's book, which first came out in 1942.

Particularly considering his father worked daily right beside the real life great grey bridge and the real life little red lighthouse.

If not, I hope the Dawson child eventually absorbed the lesson of that little book more directly, by learning more of his late father's own little Manhattan Project between 1940 and 1945.

Both the example of the book's story and the story of Henry Dawson's tiny Manhattan Project demonstrate to small children the reminder that a determined few, no matter how small in number or in power, can light up the whole world for the better .

And that little children shouldn't give up either, at the first hurdle...