Showing posts with label baby patricia. Show all posts
Showing posts with label baby patricia. Show all posts

Monday, December 31, 2012

The re-invention of a military-only antiseptic into "bedside penicillin for all" creates a global beacon of hope for a world at war

the tiny stone the builders rejected
Despite the self-centred claims of physicists, the greatest benefits to humanity have generally been ardently pursued (invented), not accidentally stumbled upon (discovered).

DNA was discovered in 1860s by an Swiss doctor, but for most of us, it was really only discovered 125 years later in the late 1980s.

That was when it began to first be successfully used to solve unsolved criminal cases, when British researcher Alec Jeffries re-invented 'DNA' as a means to definitely identify biological evidence left at the scene of a crime.


The great medical pioneer Joseph Lister clearly re-invented carbolic acid, when he took it from just one of many industrial solvents and turning it into a global life-saver.

Paul Gelmo "invented" sulfa as man-made chemical in Vienna in 1908 and it was routinely patented in 1909 by Bayer the chemical giant hoping it might yet be a useful chemical intermediate reagent.

But not until Gerhard Domagk , also of Bayer, who systemically tested every one of his firm's new chemical creations for its medical potential, was its life-saving abilities "discovered".

But I still hold this to be a case of re-invention.

 It took an awful lot of grit and determination during the Great Depression to waste scarce company money by systemically and thoroughly testing every one of the thousands of chemicals Bayer made, on then very remote possibility one might have medical applications.

The Nobel committee obviously agreed with me - giving Domagk the inventor and not Gelmo the discoverer the Nobel Prize for sulfa.

Alexander Fleming accidentally discovered penicillin in1928 and "discovered" it was only useful as a military-style antiseptic.

In 1940, Florey and Chain accidentally discovered that penicillin also might work as a systemic.

But like Fleming (by 1940) ,they still choose to emphasize its rather limited application against combat wounds infected by staph bacteria : a tiny, tiny, TINY proportion of all the deaths caused by WWII.

They were hardly alone : I was amazed to discover in my research that I could find no penicillin-making researcher between 1928 and 1945 who first put their penicillin to work as a human systemic life-saver, before they also tried it on localized wounds.

With one crucial exception: Henry Dawson.

In October 1940, months ahead of the schedule that he and his three fellow researchers had already worked out, he choose to inject systemic penicillin into two young men suffering from invariably fatal endocarditis.

At least one of the men - unexpectedly - lived.

It wasn't because of Dawson's penicillin : at an estimated 8 units per mg, it was about .56% pure.

Useless Junk ? Or Love, Hope and Charity ?


The rest (99.44%) was junk - or as I like to emphasis : "99 and 44 100ths percent pure love....hope... and charity" -- bedside penicillin.

A good bedside manner has probably saved more lives throughout history than all but a tiny handful of medications.

I contend that Dawson deliberately used his tiny amounts of home-made penicillin as part of his traditional clinician's bedside manner, to rally his patients' own body defences against their disease.

As prove, I offer up Gladys Hobby, a fellow member of his tiny team, who said she daily walked through Henry Dawson's wards, showing the patients the growing penicillium in flasks, hoping their rising interests in their treatment might rally their psychic resources.

Dawson was not content to reserve his invention of "bedside penicillin" to the handful of endocarditis patients that his small home-made supply could hope to treat.

So Dawson quickly told a convention of his colleagues (the world's top clinical researchers) that natural penicillin had "unlimited possibilities", thousands times stronger than the then acclaimed synthetic sulfas, but without their toxic side effects and inability to work well in blood and pus.

These researchers took his claims home to their labs all over the world.

Meanwhile popular media, like the New York Times , Newsweek and the wire services, spread his gospel throughout North America.

He tried to get the American government - in 1941 -(and by extension all Allied governments) to take over the production of penicillin form Big Pharma and mass produce it themselves in quantity.

Instead, wartime government bureaucrats, who were themselves paid consultants to Big Pharma , censored Dawson's conventional scientific methods to spread his good news - by restricting his access to scientific journals and restricting what he could say at scientific conferences.

But in wartime, person-to-person gossip becomes the new telegraph.

So Dawson was able to keep on spreading the word until most all of the doctors in metropolitan New York and beyond had heard of his unexpected successes with systemic natural penicillin, curing incurable endocarditis , the "Gold Standard" of infectious diseases.

Penicillin , he said, didn't have only a limited wartime role, limited to just being applied to local staph infections in combat wounds or to cure self-inflicted military VD cases.

He said it  had unlimited possibilities and could cure many of the diseases that plague a peacetime nation or a multi-million man wartime military --- if only government bureaucrats opened their eyes, their hearts and their pockets and gave it a "fair go" .

When the world's general populace, after the story of Baby Patricia broke worldwide, catch Dawson's "vision thing" , governments were forced to play catch up in the production of actual penicillin.

Meanwhile, they too caught Dawson's "vision thing" and governments all over the world turned their propaganda machine full blast to tout penicillin as a beacon of future health and hope for all , if only the Allies win this war.

The key change in the Allied governments' approach was that "for all" as it became clear that the voters did not agree with an Allied war effort that deliberately limited the supply of life-saving medicine and then triaged the world into the people worth saving and those not worth saving.

That - they said - sounded awfully familiar : wasn't that also Hitler's line ?

Well it was certainly Modernity's line : the  methods of instrumental rationality ruled all the modern nations from America to Germany.

By contrast, Dawson's general systemic was 'general' in the widest sense of that word.

 He thought it was particularly important in a Total War against Absolute Evil to give - and be seen giving - life-saving health care and food & shelter to all : it  was the best single reason why people should be willing to fight and die for the Allies' cause.

And seventy five odd years later, was he not right ?

Penicillin has a powerful mystique that tens of thousands of other useful medications ,combined, can't hope to match.

Dawson's crusade to make his inexpensive, abundant, safe "bedside penicillin" a commonplace at hospital beds the world over , in war and in peace , is the major reason we grant penicillin that mystique....

Tuesday, December 18, 2012

Politics as the authoritative "prioritizing" of values

A Canadian (but not Canada) morally defines wartime penicillin
There is a broad academic consensus as to the best way to differentiate political bargaining from economic bargaining.

That consensus says that "prices" are used to come to an informal economic agreement as to the allocating of scarce resources between alternative uses.

But politics authoritatively allocates (rations/triages) scarce resources between alternative uses.


Politics does formally what economics does informally : it passes a laws that directs that the allocating will be done by fiat and force, if need be.

But this consensus explanation merely says how the two different forms of allocation will be done.

(Either by voluntary agreement as to how one chooses to spend one's own money, or by resources being allocated at the point of a government gun if need be.)

If does not say why the government has made its allocation decisions it has made.

(We already know that Economics has made its bargains based on the differing economic values the various differing players assign to various differing goods and services.)

So normally, the consensus view has to add that politics has made its decisions and bargains based on values.

This hardly settles much : I believe it needs to be said that the political values in question are ALL moral values - albeit often expressed in terms of economic values.

And it almost goes without saying that in the political bargaining process, various bodies of political players place differing weight on different moral values and that these bodies of political players have quite different political bargaining power.

Some are large in number but have little wealth, valuable skills or organizing cohesion.

Others are very small in number, but are very wealthy, articulate, skilled in influencing governments/public opinion, and are very united in their position vis vis certain valued vales.

Most bodies of political voters fall somewhere in the middle of these positions and in fact their political bargaining strength varies widely over time and over various issues.

In addition, all these bodies agree - albeit reluctantly - they they need the others, if society and the economy are going to keep on working : thus their bargaining positions are not absolute but will settle  - if need be - for half a loaf.

This is why I say the real hard bargaining in politics occurs over the priority we as collections of political bodies give to different moral values.

Politics is always and only about winning over 'Hearts and Minds'.

And in an earlier post, I suggested why such hard political bargaining gets more - not less - intense during times of Total War.

So, to recap that earlier blog post, some of us value very highly the giving of scarce penicillin to paratroopers with a case of the Clap, so they can go back 'on strength' in two days and possibly die in the next big battle, so our own son won't have to be 'called up' in their place.

Others of us feel that a severely wounded and infected soldier who has already fought bravely in battle is more worthy of the scarce penicillin than some paratrooper deliberately cheating on his wife without a condom in some Naples brothel, hoping thus to avoid dying in an upcoming battle by being in hospital for two months with the traditional VD treatment.

We value this severely wounded hero's contribution greatly and admit we had made a tacit bargain with him to say we stay-at-homes would give him the best possible medical care if he should be wounded while defending us stay-at-homes somewhere overseas.

So we feel we must honour that bargain, despite the fact that even if our severely wounded hero is cured of his infection and lives, he will be quickly released from the army and given a small pension for life (paid for by us staying safely at home), as he will remain too permanently injured to be a good soldier or even a good factory worker.

This in a nutshell and without a lick of exaggeration , was the moral values that the Allied world debated over in the summer of 1943 - at first, solely among the well-to-do fat old men running the war and then later - post Baby Patricia - among the entire Allied population.

As the moral value of wartime penicillin went, so went Modernity - and post Modernity


In the end, it was Henry Dawson, Robert Pulvertaft, Rudy Schullinger and Dante Colitti 's chivalrous values that were prioritized, not the modern values of Winston Churchill, Howard Florey, Alfred Richards and Lewis Weeds.

And in doing so, our world quietly slipped out of the Age of Modernity and into the post Modernity Age....

Tuesday, July 27, 2010

Baby Patricia & Penicillin in Comic Book

In 1944, True Heroes Comic Books featured the inspiring story of Dr Dante Colitti  saving the life of two year old baby Patricia Malone, August 11th 1943, with some penicillin that he, the child's father and the Hearst media empire had wheedled out of a hard-nosed American medical establishment.

This was the event that made penicillin known world wide, virtually over night after 15 years of being ignored.

Colitti's hospital and Dr Dawson's hospital shared the same catchment area for patients, being only a mile apart.

 News of Dawson's cures, that Spring, of a number of women with the incurable disease of SBE  had spread like wildfire among the patients and staff of both hospitals , leading to Colitti trying the stuff on his dying young patient...

Monday, January 18, 2010

Dr Harry Haiselden, "The Black Stork" doctor








About a dozen years ago, I read Professor Martin S Pernick's book, "The Black Stork", which I consider the best single account of the eugenics movement that I have yet found.

This, despite the fact that the book is ostensibly only about a small forgotten footnote to the overall story of Eugenics, which covered a century in time and and had powerful support in all continents.

I read it, as I said, a dozen years ago - before I had 'always on' high speed internet and before Google.

Now when I read, I constantly go to my laptop and onto Google to expand on points of interest.

This week I started re-reading The Black Stork and went to Google after quickly - too quickly ! - looking through the book's pictures and not seeing a single portrait of the subject of the book - Dr Harry Haiselden.

Google seemed to have none of Haiselden either - though his story is on many websites on eugenics, ethics, the disabled, etc .

I thought how hard it was to write a biography of someone long dead, who you never knew, without a lot of good photographs .

It helps you feel that you can see into your subject's soul through their eyes, I suppose.

I was thinking mostly of my own subject, Dr Martin Henry Dawson, but also of Professor Pernick and his subject, Dr Haiselden.

I dashed off a quick email to Dr Pernick on this point and settled in to re-read the book.

It is foolish to dash anything off - and these days emails leave no chance to correct things between writing them and popping them in a mail slot a day later, as old fashioned paper letters allowed.

Of course, in a half hour I had remembered enough of Haiselden's story to realize that he had played himself in his famous film , The Black Stork, cast as Dr Dickey, ( a name from his mother's side of the family).

He was unnaturally attached to his mom and hated his dad .... and possibly hated having to carry his dad's name as well.

So we actually had a dozen photographs of Haiselden -- as poor quality movie frames - in the book and on Google - just not labelled as such.

Just now, glancing through the book's photos more slowly, I realized I had made a further mess of it .

The famous newspaper 'two head' photo of the mother (Anna Bollinger) of Haiselden's first 'victim', did not include her spouse as the other person in the picture, as I had assumed.

Instead, it was her doctor - Haiselden.

I had glanced through the centre photos in the book far too quickly, before settling in to read Pernick's sophisticated arguments.

But I think I made an interesting mistake.

Conventionally, such a 'two head photo' in such a story would be of the two parents, with the doctor in a separate shot - perhaps with his patient.

I am thinking of the pictures of Baby Patricia with her two parents, filling newspaper pages all over America, in August and September 1943 and again in 1944.

In the case of the Bollinger baby being 'encouraged' to die at birth by Dr Haiselden, mom and doctor seem to be the only two people worth photographing, in the eyes of The Chicago Daily Tribune editors.

Clearly we might think that in 1915, society regarded the fate of children severely handicapped at birth as a matter for the mother mostly - with neither her spouse, family or priest/minister to help her make her decision - that was for a scientist cum doctor.

But this editorial decision on the part of the Chicago Daily Tribune may have simply reflected their industry's efforts to cement daily newspaper reading among women, the major buyer of the goods advertised in daily papers.

"Women's Pages" and Sob Sister stories were very much part of this effort - and we might so view this unusual decision to leave the dad out of the photo, in this light.

My point is we just don't know, from a position ninety five years later - either or both position are tenable.

So, at the top of this blog entry is a cropped photo of the very good looking (but never married) , bundle of contradictions, Dr Haiselden.

Then below, the original full photo of him along with Anna Bollinger....

I'm off to eat crow and apologize to Dr Pernick !

@ArcadianRecord





Saturday, August 8, 2009

Janus Manhattan


It is no longer the world's biggest city
but it is still the world's most important
city.

The most power-filled city on Earth but
the most hope-filled city as well.

Home to Wall Street and Ellis Island.

Organizational birthplace of Eugenics and
home to more Jews than any other city on the planet.

The world's biggest life-ender was birthed here, as was the world's smallest (and best) lifesaver -- at the exact same time in history, in the same small neighbourhood.

The little boy and baby patricia both were born here.

Epicenter of an inhumanly endless megalopolis stretching from Portland Maine to Richmond Virginia, it is also home to hundreds of tiny ,distinctive, fiercely independent neighbourhoods.

Janus Manhattan.

The rest of the world is forced to function as any illiterate must, to become very very good at reading the face of this inscrutable giant, because the continued existence of our planet might depend on our skill at reading it correctly.