May the small, like the Big, always be with us....

A blog that celebrates the small, in a world that drinks the Kool-Aid of Bigness ...

We certainly don't need a new blogger celebrating the Big : the world already has seven billion mouths doing that daily.

The Big are in absolutely no danger of disappearing, certainly not from our culture and not even as a result of rapid changes in the global environment.

The small also are hardly in danger of disappearing in the world's rapidly changing environmental situation.

In fact, when the environment suddenly changes they always do much better than bigger beings : always have and always will.

But culturally, the small are very much a collection of Rodney Dangerfields : never getting anywhere near the respect they deserve.

As microbe beings too small for us to see with our naked eyes, they keep this whole biological ball of wax afloat : without them the world would be a barren chunk of rock.

Small but visible species of plants and animals are the next layer of beings that help make this rock a nice place to live for us, those human parasites at the topper-most top of the whole food , air and water chain.

Within the human species and culture, 'small' humans (aka the poor, tired and huddled) still tend to be treated with general indifference.

Small places and institutions are still quickly dismissed as yesterday's entities.

This blog , by contrast, is devoted to reminding us of the comforting safety factor that comes with the diversity and flexibility of a world with many small beings and entities all exploring different options.

It seeks also to remind us of the danger of putting all our intellectual eggs in a few Big (tired) baskets as we face a rapidly changing world.

And  it seeks to remind us of the sheer joy we get out of being immersed in an incredible variety of experience.

And it intends to warn us of the danger of returning to being gray-suited citizens of a few unitary-minded empires that all look and act and feel alike as they march eagerly towards their environmental doom....

The irony of 1945's twin triumphs ...

1945 was , on any account, an extraordinary year, not the least for its twin scientific triumphs.

At the time, it was almost universally held that the Man-made Bomb was the way of an atomic future so bright we'd have to wear shades .

By contrast, 1945's new Microbe-made medicine (natural penicillin) was viewed as but a temporary anomaly, a dusty throw back to the outdated caldron practises of medieval midwives.

But more than a half century later we are no longer so sure of all of this.

Atomic energy has not at all fulfilled its early promise.

Meanwhile, microbiology and biotechnology (descendants of 1945's natural-produced penicillin) have far outshot their 1945 rival, synthetic chemistry.

So today, with 20/20 hindsight, while 1945 can still feel like the apogee of the Modern age,it is also revealed as its very nadir.

Because 1945 is now seen as the birthday of our present post-Modern age.

In which case, Henry Dawson's twin follies of advocating on behalf of small individuals and on behalf of small microbes can be seen as promoting a distinguishing hallmark of postmodernity.

For few of us, under the age of eighty, devote much energy these days to replacing our current rainbow of many small cultures with a return to yesterday's dreary unitary monoculture of constipated WASP-dom.....

Social Darwinism turns Peace into Undeclared War...

The attributes of the Age of the Big (Social Darwinism Mk I) makes the idea of contrasting it with the concept of the War of the Big (Social Darwinism Mk II) a moot point.

This is because the Social Darwin idea of reducing all Life to an unceasing, total, struggle for life or death means that only a formal declaration on paper could separate Darwinian War from Darwinian Peace.

It was always assumed , without much proof, that in this struggle the big would  inevitably triumph over the small and then the ever bigger would do likewise over the merely 'big' .

By contrast ,Henry Dawson championed the small all his life - it must have come almost naturally to him, with his coming from a Canadian province that was increasingly viewed as too small to be relevant to Canadian values.

But he also noticed in his scientific investigations that while the big did thrive in stable circumstances, the small could still at least survive in hidden niches.

But in non-stable times, the big (over-extended) broke up,  while the small (insured against normal hard times) took it all in stride.

Rather than modern science quickly dismissing Life's small as just part of evolution's dusty, distant beginnings, he felt they should give the small a second glance - and a second chance.

He extended this in the 1930s to those judged chronically ill and second rate and then, in the war years , to those American young people with SBE who were judged to be 'life unworthy of expensive medical care during a military crisis' .

Modern science had no time for his theory - his championing  of the small was viewed as a damning folly from a medical scientist with an otherwise worthy medical career.

But post modernity science is largely shaped around the concept of reality's inherent complexity and diversity : admitting that reality will always consist of the mixing together of large and small phenomena and large and small beings.

In this long view, Dawson's folly begins to look quite prescient ...

Wartime Manhattan's Projects : big Little Boy versus the tiny ampoule that saved little Patty Malone

The Little Boy atomic bomb that dropped on Hiroshima was a very Big Bomb indeed : 5000 kilograms , 300 cm long, by 70 cm wide and 70 cm deep.

Long and thin : hence Little Boy.

 Big Science needed tens of thousands of workers to build it.

By contrast, the tiny ampoule of natural penicillin that saved the life of  little baby Patty Malone was only 5 grams in weight, .7cm by .7 cm by 3 cm in size.

It was thus 100 times shorter in length and width and thickness, though it too was long and thin in appearance.

 And since its density was also surprisingly similar to that of Little Boy, it appropriately weighed 5 grams : a million times less (100 x 100 x 100 = 1 million).

Small science indeed.

Particularly when we recall that natural penicillin is actually made in a fungus factory that weighs about 70 pico grams (pico : one trillionth of a gram !) .

That is about a billion trillion times less the weight of what it would require for humanity to  make the basic machinery and basic chemicals for chemists to synthesize penicillin.

The fungus only requires a bit of dirty water and a bit of decaying organic debris.

America's big bombers carried both the Little Boy bomb and the ampoules of penicillin : one went off to Hiroshima, the other also went all over the world  to save lives.

 However its first mercy run was from Brooklyn New York to Macon Georgia, to save Anne Shirley Carter.

A mighty big plane and a mighty long journey for such a small little ampoule but if any taxpayer complained, they were very careful not to do it publicly.

Could any two projects - anywhere - anytime - have been more different ?

Dawson's penicillin 1940-1945 : made in the Public Domain , FOR the Public Domain

Howard Florey's penicillin 1940-1945, by way of pointed contrast, was Pure penicillin for Purely military use only.

He believed that penicillium were tiny ancient life  and so , by definition , linear progressive Evolution's "Yesterday's Men" .

He was sure civilized scientific Man was bound to make penicillin better and cheaper than some slimy mold in a sort of  witch's caldron .

But, in fact , chemists actually needed hundreds of millions of dollars - in 1940s dollars - together with tens of thousands of tons of structural and stainless steel  to make a whole series of chemical factories, just to get started on making penicillin.

All those big plants, together with lots of staff, a whole lot of energy and many corrosive solvents were Man's way of making penicillin.

They needed to be build expensively strong in order to safely apply high pressure and high & cold temperature over and over in many steps.

All this to replicate what a incredibly tiny fungus cell (sixty pico grams in mass) could produce at ordinary temperatures and ordinary pressures out of a little dirty water and a bit of decaying organic material.

That tiny fungus factory weighed about one billion trillion times less than all of the factories needed to make the basic chemicals that went into the final penicillin synthetic factory.

So if you thought that perhaps the tiny fungus could do the job better and cheaper, then you were with Dawson.

Now, just as how you viewed the possibility of the continuing viability of small beings coloured the type of penicillin factory you preferred, it seemed to also colour who you thought the penicillin should help.

So, Florey: big factory penicillin for big armies only ; Dawson : small factory penicillin for small people everywhere.....

Crude Penicillin and Bacterial Transformation : two neologisms of Henry Dawson

Henry Dawson was far from a wordsmith but he did coin two neologisms that have survived in today's scientific and historical lexicon.

One was "bacterial transformation" (a form of HGT, horizontal gene transfer -- basically non-Darwinian inheritance) and the other was "crude penicillin".

To explain this latter term is is best to recognize it is really a term of scientific and political polemics.

Let us imagine a British Empire in the early 1940s, badly hurting a time of war because it had refused to accept a fact known for at least two centuries.

That fact was that the most natural , most versatile and cheapest way to solve the naval and merchant ship scurvy crisis was with a good supply of citrus fruit kept on board.

Marshalled against this fact discovered by James Lind was an array of louder, better educated and greedier voices.

What they were telling the government and the media and future historians was that Britain's dying sailors must simply be patient.

In its own sweet time an expensive synthetic vitamin C was sure to emerge, fully patented, from one of the nation's chemical firms.

One expensively patented , tasteless , pill would solve the human daily needs for vitamin C - as would other patented pills for all our daily food intake.

We needn't waste time away from our desks on meals when a glass of water and a big handful or two of pills would solve the problem.

Against this chemical boasting would be an array of people saying that they looked forward to meals - perhaps even more than sex and certainly far more than they looked forward to work.

Others would point out that citrus fruit and vitamin C rich vegetables are found world wide - are both cheap and abundant - a security of supply issue.

They would further point out that the deadly delay in solving this sea-going crisis for the Empire was simply down to greed and ambition.

The delay was down to some ambitious scientists seeking the glory for having synthesized something Mother Nature already provided and to some greedy chemical companies wanting a profitable patent to exploit.

These claims against patented vitamin C pills are so damning  a master scientific polemist would be called upon to defend Chemistry.

A scientific polemist like Howard Florey because he, too, was a bit of a neologism creator : he was the first person to talk about impure and pure penicillin, for example.

An orange ,he could point out, could potentially be a dangerous source of vitamin C because it was an impure  source of the needed vitamin (in the sense that vitamin C only made up a tiny fraction of one percent of the orange by weight).

In a 1940s culture where the middle class had more education than common sense, this would be effective arguing : everyone wanted cleanliness and purity.

Henry Dawson immediately caught onto this "Only I know how to make pure safe penicillin" line of attack from Florey's very first article on penicillin and quickly mounted a rebuttal.

And he did so in the august pages of the New York Times on May 6th 1941.

In effect, he said an orange can be one of four things, as regards to being an safe source of vitamin C.

It could be unsafe because both the orange and its vitamin C are potentially dangerous.

It could be safe because both the orange and its vitamin C are harmless to consume.

It could be unsafe because vitamin C is potentially dangerous, perhaps in larger quantities.

It could be unsafe because the orange itself was potentially toxic.

The only thing to do , as always , was less talk and more experiments.

He tested impure penicillin (penicillium juice) upon himself and upon some human patients and found it perfectly safe.

He boldly called his successful medicine "crude penicillin" --- naturally made penicillin happily bathing its its naturally produced impure bath.

it was a medicine made by microbes and offered up to all, free in the Public Domain : thus meeting Florey's subtle corporate agenda head-on.

Ironically, years later, it was revealed that pure penicillin itself  was potentially unsafe (unlike the rest of the harmless penicillium juice) because when pure it can be given in large enough amounts to result in sudden penicillin allergy deaths !

Pure members of the aryan races might still believe they can only survive on pure penicillin and pure vitamin C but the rest of this polyglot world still likes to take its daily nourishment 'crude' , dining around the table with family and friends.

It hasn't seemed to harm the seven billions of us so far....

Are the small just a tiny part of the Modern past or a vital part of the Postmodern future ?

Two hundred years from the event, historians will be telling classrooms that when it comes to exam time, they should remember that WWII boiled down to just one issue.

One - scientific - issue.

Were the small to be considered just a tiny part of Modernity's dusty past or were they to be a vital part of the (postmodern/multi-coloured) future ?

In early 1939 , on one side was virtually all of the world's educated.

On the other, was Henry Dawson : and that was his folly.

By late 1945 , Henry Dawson was dead and gone and so his current opinion was irrelevant.

But many of the world's younger educated had moved - under the course of many events - one begun by Henry himself - to doubt their parents' and grantparents' position on the matter.

For if the smartest pundits of the war's end were sure that 1945 represented the apogee of modern bigness , by about 1978 leading commentators are just as sure it actually represented Modernity's nadir and the birth of our present day Postmodernity.

But Dawson's all-out efforts to defend the small under the assault of WWII values caused his premature death, so he wasn't around in his mid-eighties to enjoy his vindication.

That to was his folly ; or his eternal glory ...