Dawson had been set to be the "invisible man", the Charles Fletcher of The Manhattan Pilot

I believe that for two critical weeks at the very beginning of the The Manhattan Project, Martin Henry Dawson was not set to be the team leader/senior investigator - in fact he was not expected to be involved at all.

The team was supposed to be led by the biochemist Karl Meyer, with someone (anyone) acting as the microbiologist to test the 'in vitro' activity of the penicillin produced , again with some doctor (anyone) from Columbia Presbyterian's eye clinic in the clinician's job  (the nominal job of Dawson on the final Pilot team) .

The penicillin pilot's aim, at that point, was simply (!) to purify and then synthesize penicillin - most of the small amounts of crude penicillin produced would have to be destroyed in crystallization (purification) experiments.

Only tiny, tiny amounts could be spared to show the resulting penicillin still retained the needed biological activity against bacteria on a glass slide or against bacteria on/in a human.

These were expected to be merely subordinate activities to the main show - "making penicillin".

Now any drug, not just penicillin, needs to be first proven safe for humans when taking internally and be available in huge amounts, before it can be injected into the body as a 'systemic' --- versus simply being dropping a bit of it into the restricted/external area around the eyeball as an 'antiseptic'.

Penicillin, in particular, quickly slips out of the body and so needs even larger amounts than most drugs to work successfully as a systemic.

This is why penicillin's first successes in Britain during the 1930 (but tragically for humanity never published), were in removing deadly bacteria from the area around the eyes.

Meyer ,working in an eye clinic ,knew these truths better than most. In fact, he did involve two doctors from his clinic to use some of his penicillin with their patients but both doctors (Von Sallmann and Thygeson) seemed dubious about its usefulness around and in the eyes (as well they should have been).

 The results were not spectacular and were published a few years later.

Eyes were saved in the early 1930s from a lifetime of blindness with treatments of diluted crude penicillin that in total must have consisted of only 1.6 Oxford units of biological activity (that is equal to one millionth of a gram of pure penicillin).

By contrast, Dawson's disease of choice to test penicillin upon, SBE, subacute bacterial endocarditis, may today require 1.6 billion units of penicillin to cure.

That is one kilogram of pure penicillin - one billion times as much penicillin.

It was known in 1940 that SBE would need an extraordinary large amount of whatever drug that could kill the bacteria in its vegetations because of the unique location of the lesions and the poor blood supply of the heart valves they rested upon- that is the problem in fact that still makes SBE the 'gold standard' of intractable infections.

All drugs to date, as of 1940, had to be used in such large amounts to kill the bacteria that they killed the patient first - because even a relatively "non-toxic" drug is deadly if used by the shovelful !

It was Dawson's genius to see that penicillin's strength was not what the popular books on it still proclaim - its ability to kill bacteria - but rather its ability not to kill the patients, even when used in extraordinarily high amounts for months at a time.

And SBE proved to be just the disease to demonstrate that fact....

@MichaelMarshallMogoesPo

Agape Science: thinking commensally : going Po

I have often said my Martin Henry Dawson project is "all about love" - all three variants of it.

Eros, romantic love, might seem a stretch.

However Dawson had seen too many fellow teenagers die in the trenches of WWI, without ever even having had a kiss or a girlfriend ,to fail to understand what a diagonsis of Rheumatic Fever meant to kids, back in those days.

Doctors and friends told parents in total earnestness, that any extra stress on their child's heart after they had had Rheumatic Heart Disease could kill them.

That meant no dancing,  or sexual intercourse or pregnancies and childbirths - all the things that make a young person's life worth living !

Patria love or philia/filial love, love of one's own family and their country, was the reason why the 'greatest generation ever'  finally went off to fight.

But patriotism isn't that high on the scale of wrong or right, in the way Jesus reckons things.

He placed agape love, the willingness to die, if necessary, for someone else's country well above the willingness to die to save one's own country.

Here America fell down .

Twenty seven times, by my count, small groups of American citizens came before their congressmen to plea for Congress to intervene militarily when their ( or the family's) homeland was invaded.

Peter only refused 3 times - American did it it 27 times between 1931 and 1941.

(Not that my country - Canada - was all that much better.)

One wonders if Japan had gone into Russia instead of Pearl Harbour would America had gone to war at all in World War Two ?

Even on December 8th 1941, FDR and Congress only went to war against Japan - it took Hitler declaring war on America to bring it out fighting against the greatest evil our world has ever known.

Dawson had already taken up arms years earlier to defend a little country from a bully and been wounded twice for his efforts and gotten the Military Cross with citation for his bravery.

But in this war, he was dying and unfit for military service overseas.

Still he exhibited agape love and agape science when he sought to save the lives of people America's leaders in science and medicine said were unworthy of much medical attention in times of war....

@MichaelMarshallMogoesPo

"Going Po" /"Going Native"/"Letting Down the Side"

I have often wondered about why Martin Henry Dawson's legacy was so quickly - and quietly - 'disappeared' after his early death.

I mean Penicillin was very big news, Rheumatic Heart Disease remained the leading killer and crippler of school age kids (well above the numbers affected by polio), DNA was becoming big news.

I think one explanation was that many of his contemporary fellow doctors and scientists felt that he had 'let down the side' or 'gone native' when he 'went Po' and tried so hard to save the lives of people that many of them considered unworthy of much medical attention at the height of Total War.

I think Dawson would argue - but only if he was forced to argue, with a gun at his head ! - that the whole point of that Total War, the whole point of the quarrel with our Japanese and German cousins, really revolved around the question 'were all lives worth saving, or only some ?'

He was sure which side the Axis was on, he thought that the Allies were on the other.

Publicly, they were - they just didn't mean to see it carried out in practise.

When Dawson did so, he exposed their inconsistencies : talk versus walk.

No one ever honors someone who reveals them to be hypocrites.....

@MichaelMarshallMogoesPo

What a difference one little substitute word can make...

My partner Rebecca said some very nice things about this, my new blog.

But I am afraid I misled her a little in describing my take on Postmodernity.

I meant to say that Modernity was a particular and peculiar form of  'Aesthetics masquerading as Science' ---- and functioning as an entire worldview and ideology.

And that Postmodernity was more than 'just' the aesthetics of contemporary painting, pop music and architecture - it was another particular form of Aesthetics and also functioning as an entire worldview and ideology.

I think I have now found a succinct way to describe the difference between Modernity and Postmodernity and it is in the new subtitle of this blog .

Taking the widest view of the term Postmodernity : converting it - but only very slightly -  from my emphasis on ethics and morality to one of aesthetics - it can be phrased as a difference in  the sort of people we find aesthetically attractive.

Today we are far more willing to see attractiveness in many more body shapes,  skin colors and lifestyles - or at least to let other people see beauty in people we don't find  that particularly attractive.

It is typical of this Postmodernity era to learn of a recent poll saying that most of us find a person of mixed color ( the tawny or coffee colored flesh tone so common in places like Brazil) as the most attractive physical type.

(Just as it is a hangover from our grandparents' Modernity era to learn that most high fashion models continue to be the icy blue-eyed blonds of  1930s Aryan wet dreams.)

My take is that between 1939 and 1945 (and in the immediate postwar period), many - but by no means all - of the middle class educated people in the most modern countries in the world changed their minds.

They decided, albeit in a subdued and inchoate fashion, that  all  life was in some sense
worthy of life and dignity and worth.

When they repudiated Eugenics (and again not everybody did) they repudiated the core tenets of Modernity --- just as Professors Adorno and Horkheimer had insisted they had to do in 1944, in their famous little mimeo-book ( Dialetic of the Enlightenment), circulating throughout the campus of Columbia University in New York City.

Currently, there is no record of what Professor Martin Henry Dawson, also at the same university at the same time, thought about Adorno and Horkheimer's claim - or in fact about virtually anything - we have no personal papers.

But in his public 'biography of deeds', he certainly acted in a postmodern fashion - giving up his life to save the life of someone (Charlie Aronson) who many American doctors considered a prime example of the fact that only 'some life is worthy of life'.

In one of those improbable coincidences that make up reality,Dr Foster Kennedy advocated that only some lives are worthy of life and that all others should be killed (at the annual meeting of the American Psychiatric Association) on the same day as Dawson first announced (at the annual meeting of the American Clinical Society) that he was trying to save the lives of the unfit, with some penicillin he had brewed up himself.

In a sense, to Kennedy's statement, Dawson merely substituted the little word "all" for "some" and then forcibly acted upon that statement, against the greatest of obstacles.

Mo only truly goes Po when somebody actually does something concrete.

 And it was Martin Henry Dawson putting PoMo thought into PoMo action that made all the difference - for Charlie and then ultimately, for all of us .....

@MichaelMarshallMogoesPo

Martin Henry Dawson, the born subordinate.

He had a number of life-changing ideas but he was too cautious and too polite to go all out in proclaiming them and his colleagues and opponents knew it.

In a metaphorical sense, he was the proverbial 'coward of the county' .

I don't think he disobeyed but one order in his entire life.

But when he did.... our whole world changed for the better, forever.

@MOgoesPO

We agree WHEN Mo started going PO, but not necessarily why

                  Martin Henry Dawson , on enlistment, 1915

My partner, Rebecca, has tried to explain the meaning behind the title of my latest blog "MO goes PO" .

All I can add is that there is overwhelming agreement that the Mo-to-Po revolution began fairly abruptly, in 1945.

You remember 1945, the end of 'double-u, double-u, two' , the so called last good war and the last good generation.

Few people have given a good account why PoMo began then, AND in the nations of the moral victors.

If the good guys are just won the war against the bad guys, why were the good guys leading the way in uneasily evaluating their own values ?

I hope "MO goes PO" succeeds in telling us why....

@ArcadianRecord

This is my new blog for my MARTIN HENRY DAWSON project

I will post the finished segments ( albeit not likely in their proper chronological sequence) here, one week after the 'final' version of each segment has had a chance to pass my 'wiggle test'.

That is to say, I will print out a reduced size, B&W 'final version' copy on my computer printer and see how it reads on paper, after it has been lying around my house a day or two.

For sometimes you catch things you didn't when the segment was on the computer screen, no matter how often you re-read and re-edited it.

In time, I will also put each of these segments in my 'MO goes PO'  public archives - my 16 GOOGLE SITES websites.

But this time, they will be in their intended chronological order, leaving blanks for the segments not yet published.

One GOOGLE SITES website for each of 15 Scenes (in three Acts)  --- plus one for the author's Afterword.

No more than 26 segments maximum per Scene - hopefully not that many ! - so I can label them from A to Z.

So their numbering will be labelled 3c and 16j etc , indicating that the first is the third segment of Act I, Scene 3, while the other is the tenth segment in the author's Afterword.

Think of it as a sort of Play or Musical covering six years (exactly - September 2nd 1939 to September 2 1945) in three hours...

I will reserve my right totally, to revise/ revise/ revise each 'final' segment - but you will at least be able to follow the revisions publicly.

@mogoespo